Yes, a denied EB-5 investor visa application can be appealed, but the course of action depends on the specific grounds for denial and the stage of the process. You may file a motion to reopen or reconsider with USCIS if there is new evidence or a legal error. In cases involving Form I-526E denials, you may also file an appeal with the Administrative Appeals Office (AAO). for denials, you can seek federal judicial review in U.S. district court. Alternatively, you may file a new petition with stronger documentation or explore other visa categories. Legal counsel is essential to assess viable options.